. 2005 Jun;58(6):640–644. doi: 10.1136/jcp.2004.022509

Table 2.

Differences in incidence of BRAF or BRAF/NRAS mutations in various types of non-cutaneous melanomas (present study) compared with primary cutaneous melanomas (from the literature)

Melanoma type	Incidence of BRAF mutation	p Value*	Combined incidence of BRAF/NRAS mutations	p Value*
Primary cutaneous melanoma	178/444 (40.1%)^10,^12,^15,^18,^20,^22–²⁸†		111/141 (78.7%)^10,^22–^24,²⁸†
Malignant melanoma of soft parts	0/7 (0%)	0.029	0/7 (0%)	<0.0001
Mucosal melanomas	2/36 (5.6%)	<0.0001	7/36 (19.4%)	<0.0001
Uveal melanomas	0/6 (0%)	0.048	1/6 (16.7%)	0.0029
All non-cutaneous melanomas	2/51 (3.9%)	<0.0001	9/51 (17.6%)	<0.0001

*Comparison of each category against primary cutaneous melanomas using Fisher’s exact test.

†Literature data were pooled from the references.