Table 5.
Immunohistochemical staining patterns of p21, p16, and p53 in patients with non-small cell lung cancer
| Cyclin D1 | pRb2/p130 | p16 | No. of patients | Group |
| − | + | + | 24 | |
| − | − | + | 22 | A (59) |
| − | + | − | 4 | |
| + | + | + | 9 | |
| + | + | − | 18 | |
| + | − | + | 6 | B (25) |
| − | − | − | 1 | |
| + | − | − | 21 | C (21) |
Group A, no or only one adverse prognostic factor; group B, two adverse prognostic factors; group C, three adverse prognostic factors.