Table 2.
HD5 expression in normal and intestinal metaplasia of the gastrointestinal tract
| N | HD5 immunostaining | Helicobacter pylori infection | |||
| Positive | Negative | Positive | Negative | ||
| Tissues with IM | |||||
| BO | 33 | 5 (15%) | 28 (85%) | 3 (27%) | 8 (73%) |
| GIM | 51 | 42 (82%) | 9 (18%) | 44 (86%) | 7 (14%) |
| Tissues without IM | |||||
| Oesophagus | 5 | 0 | 5 (100%) | NA | NA |
| Stomach | 16 | 0 | 16 (100%) | 9 (56%) | 7 (44%) |
| Small intestine | 20 | 20 (100%) | 0 | NA | NA |
| Colon | 20 | 0 | 20 (100%) | NA | NA |
BO, Barrett’s oesophagus; GIM, gastric intestinal metaplasia; HD5, human defensin 5; IM, intestinal metaplasia; NA, not applicable.