Figure 2.
Results of hybridisation of the EWSR1 dual colour breakapart probes. Tumour cells of (A) a Ewing’s sarcoma and primitive neuroectodermal tumour, (B) a desmoplastic small round cell tumour, and (C) a clear cell sarcoma show one fusion, one orange, and one green signal pattern, indicative of a rearrangement of one copy of the EWSR1 region. (D) Tumour cells of an alveolar rhabdomyosarcoma show two fusion signal patterns, reflecting the two intact copies of EWSR1.