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. 2005 Oct;58(10):1076–1080. doi: 10.1136/jcp.2004.025585

Figure 2.

Figure 2

 The results of protein expression and gene amplification of EGFR (epidermal growth factor receptor) and HER2 in adenocarcinoma. (A) Partial EGFR expression over part of the cell membrane in bronchioloalveolar carcinoma (BAC). (B) EGFR expression was seen over the entire cell membrane in the invasive component of adenocarcinoma with mixed subtypes (MX). (C) An EGFR gene cluster (more than six gene copies) seen in the case shown in (B). (D) Absence of HER2 expression in the membrane of a BAC lesion. (E) HER2 expression seen over the entire cell membrane in the invasive component of MX. (F) More than six gene copies of HER2 seen in the case shown in (E).