Table 3.

 Light microscopic findings in the two groups

Variables	First biopsy		p Value	Second biopsy		p Value
	Group I (n = 9)	Group II (n = 12)		Group I (n = 9)	Group II (n = 12)
ISKDC			NS			0.015
I	0	0		2	0
II	0	0		6	2
IIIa	6	9		1	6
IIIb	2	3		0	3
IVb	1	0		0	1
AI	7.9 (0.7)	6.8 (0.3)	NS	2.9 (0.4)*	6.0 (2.1)	0.001
CI	0.4 (0.2)	0.8 (0.3)	NS	0.4 (0.2)	1.8 (0.3)†	0.012
TI score	1.0 (0.5)	1.7 (0.4)	NS	0.4 (0.2)	3.1 (0.8)	0.009
Crescents (%)	21.9 (5.8)	12.4 (3.3)	NS	1.4 (1.4)*	13.9 (5.0)	0.019

Values (except for ISKDC results) are mean (SEM).

*p<0.01 and †p<0.05 when compared with the first biopsy.

AI, activity index; CI, chronicity index; ISKDC, International Study of Kidney Disease in Children; NS, not significant; TI, tubulointerstitial.