Table 1.
Case | Site | Type of granuloma | IHC | Diagnosis |
1 | 1 of 10 lymph nodes | Necrobiotic | Negative | Necrobiotic granulomatous |
2 | 9 of 20 lymph nodes | Necrobiotic and epithelioid granulomata (1 node); necro-biotic granulomata (1 node); epithelioid granulomata adjacent to metastases (5 nodes); epithelioid granulomata without associated metastatic carcinoma (2 nodes) | Positive | Metastatic tumour necrosis with granulomatous inflammation |
3 | Stroma | Necrobiotic | Positive | Tumour necrosis with granulomatous inflammation |
4 | 5 of 9 lymph nodes | Necrobiotic (2 nodes); epithelioid (3 nodes) | Negative | Necrobiotic granulomatous lymphadenitis |
IHC, immunohistochemistry.