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. 2005 Aug;58(8):826–832. doi: 10.1136/jcp.2005.025718

Table 2.

 Genes showing a significant ⩾1.5 fold change between cases and controls in microarray experiments

GenBank accession number Gene name (mRNA) Gene symbol Fold difference (array) p Value Taqman assay ID Fold difference (PCR) p Value
NM_020325 ATP binding cassette, subfamily D (ALD), member 4, tv-4 ABCD4 3.398 0.00257 Hs00245340_m1 1.825 0.0019
NM_002741 Protein kinase C-like 1 PRKCL1 2.288 0.00438 Hs00177028_m1 2.669 1.09×10−5
NM_021134 Mitochondrial ribosomal protein L23 MRPL23 2.175 0.00135 Hs00221699_m1 4.032 1.25×10−6
NM_001558 Interleukin 10 receptor α IL10RA 0.252 0.00225 Hs00387004_m1 0.395 2.34×10−12
NM_006110 CD2 antigen (cytoplasmic tail) binding protein 2 CD2BP2 2.311 0.00158 Hs00272036_m1 2.411 2.6×10−4
NM_000177 Gelsolin (amyloidosis, Finnish type) GSN 2.141 0.00105 Hs00609276_m1 1.83 6.23×10−7
NM_006702 Neuropathy target esterase NTE 2.877 0.00043 Hs00198648_m1 6.409 1.31×10−12
NM_002696 Polymerase (RNA) II (DNA directed) polypeptide G POLR2G 2.264 0.00372 Hs00275738_m1 3.407 3.69×10−6
NM_004813 Peroxisomal biogenesis factor 16, tv-1 PEX16 3.004 0.00213 Hs00191337_m1 1.758 0.0126
NM_015636 Eukaryotic translation initiation factor 2B, subunit 4δ, tv-1 EIF2B4 2.414 0.00125 Hs00248984_m1 1.882 1.8×10−5
NM_004953 Eukaryotic translation initiation factor 4γ1, tv-5 EIF4G1 3.081 0.00177 Hs00191933_m1 2.964 7.63×10−13
NM_016476 APC11 anaphase promoting complex subunit 11 homologue ANAPC11 3.278 0.00219 Hs00212858_m1 2.366 3.5×10−6
NM_002598 Programmed cell death 2, tv-1 PDCD2 2.052 0.00266 Hs00751277_sH 1.887 1.3×10−4
NM_003685 KH-type splicing regulatory protein (FUSE binding protein 2) KHSRP 2.366 0.00139 Hs00269352_m1 1.64 0.0022
NM_015399 Breast cancer metastasis suppressor 1 BRMS1 2.246 0.00219 Hs00363036_m1 1.598 0.003
NM_031412* GABA(A) receptor associated protein-like 1 GABARAPL1 2.358 0.00046 Hs00744468_s1 1.838 0.0097
NM_004655 Axin 2 (conductin, axil) AXIN2 0.351 0.00056 Hs00610344_m1 0.780 0.023
NM_019051* Mitochondrial ribosomal protein L50 MRPL50 0.427 0.00409 Hs00745120_s1 0.815 0.0019
NM_005103* Fasciculation and elongation protein ζ1 (zygin I), tv-1 FEZ1 0.336 0.00007 Hs00192714_m1 3.485 2.3×10−6
NM_002093 Glycogen synthase kinase 3β GSK3B 2.294 0.00238 Hs00275656_m1 0.763 0.0015
NM_005098 Musculin (activated B cell factor 1) MSC 0.374 0.00121 Hs00231955_m1 1.118 0.036
NM_138325 Paired basic amino acid cleaving system 4, tv-6 PACE4 0.473 0.00414 Hs00159844_m1 2.093 1.2×10−4
NM_003584 Dual specificity phosphatase 11 DUSP11 0.366 0.00005 Hs00186058_m1 1.725 0.134
NM_002483 Carcinoembryonic antigen related cell adhesion molecule 6 CEACAM6 0.301 0.00048 Hs00366002_m1 1.585 0.182
NM_019051* Mitochondrial ribosomal protein L50 MRPL50 0.427 0.00409 Hs00747929_m1 1.136 0.178
NM_030575 Hypothetical protein MGC10334 MGC10334 2.584 0.00118 Hs00257998_s1 1.724 0.067
NM_031412* GABA(A) receptor associated protein-like 1 GABARAPL1 2.358 0.00046 Hs00740588_mH 0.93 0.127
NM_007175 Chromosome 8 open reading frame 2 C8orf2 2.554 0.00206 Hs00200360_m1 1.198 0.052
NM_032118 Hypothetical protein FLJ12953 FLJ12953 1.931 0.00309 Hs00259557_m1 1.139 0.203
NM_004879 Etoposide induced 2.4 mRNA EI24 0.45 0.00181 Hs00747550_m1 1.03 0.085
NM_079834 Secretory carrier membrane protein 4 SCAMP-4 2.8 0.00069 Hs00365263_m1 1.586 0.173
NM_022145 Leucine zipper protein FKSG14 FKSG14 0.345 0.00205 Hs00259557_m1 1.212 0.345
NM_005103* Fasciculation and elongation protein ζ1 (zygin I), tv-1 FEZ1 0.336 0.00007 Hs00363763_m1 1.062 0.41
NM_003409 Zinc finger protein 161 homologue ZFP161 0.415 0.00146 NA NT NT
NM_007075 JM5 protein JM5 2.383 0.00172 NA NT NT
NM_005345 Heat shock 70 kDa protein 1A HSPA1A 3.198 0.00003 NA NT NT
NM_017616 Hypothetical protein FLJ20004 FLJ20004 2.679 0.00237 NA NT NT
NM_020663 Ras homologue gene family, member J ARHJ 2.277 0.00346 NA NT NT

mRNA transcripts identified by array and differential expression confirmed by real time PCR are shown in bold.

The table also shows confirmatory Taqman assay numbers (Applied Biosystems UK) and fold changes by real time PCR.

*Transcript variants of particular genes.

NA, not available; NT, not tested; PCR, polymerase chain reaction.