Table 2.
Neuron count in the RGC layer. Distribution of neurons in the RGC layer for each area evaluated—ie, central, intermediate and peripheral in percentage of the total number of neurons and mean neuron size in relation to TONL
| Number of neurons (SEM) | Neurons per counting area in % of Nges; ([% of neurons ≥ 80 μm2]) | Mean neuron size (μm2) (SEM) | ||||||
| TONL (number of animals) | Mean total number | Central | Intermediate | Peripheral | Mean size | Central | Intermediate | Peripheral |
| K (n=23) | 230 236 (3711) | 40.8 [54.4] | 33.5 [54.0] | 25.7 [56.9] | 99.41 (0.40) | 95.61 (0.56) | 98.19 (0.68) | 107.03 (0.91) |
| P (n=10) | 220 866 (5877) | 41.6 [53.1] | 34.1 [55.0] | 24.7 [55.3] | 98.27 (0.59) | 93.80 (0.81) | 97.66 (0.98) | 106.56 (1.41) |
| 2 cN/6 min (n=3) | 229 123 (14 519) | 37.6 [51.6] | 33.9 [63.6] | 28.6 [51.3] | 99.54 (1.08) | 99.25 (1.76) | 96.11 (2.01) | 102.41 (1.82) |
| 2 cN/15 min (n=3) | 217 499 (4434) | 39.9 [56.7] | 33.3 [57.5] | 26.9 [59.0] | 102.44 (1.1) | 98.92 (1.55) | 100.91 (1.81) | 109.56 (2.55) |
| 2 cN/30 min (n=3) | 223 770 (7890) | 41.6 [63.4] | 33.7 [59.3] | 24.6 [55.9] | 105.91 (1.13) | 103.63 (1.54) | 106.26 (1.99) | 109.27 (2.61) |
| 5 cN/1 min (n=8) | 222 946 (8259) | 41.8 [58.6] | 33.4 [60.8] | 24.8 [65.5] | 103.89 (0.66) | 97.19 (0.89) | 103.30 (1.14) | 115.96 (1.55) |
| 5 cN/6 min (n=7) | 213 350 (10 037) | 39.1 [56.1] | 35.2 [58.1] | 25.7 [58.8] | 104.52 (0.85) | 100.29 (1.25) | 103.98 (1.43) | 111.66 (1.86) |
| 5 cN/15 min (n=6) | 198 095 (9809) | 39.8 [56.1] | 34.1 [56.7] | 26.1 [60.6] | 105.78 (0.91) | 100.54 (1.28) | 105.17 (1.55) | 114.56 (2.06) |
| 5 cN/30 min (n=4) | 156 425 (8517) | 41.8 [49.3] | 33.8 [50.2] | 24.5 [50.8] | 97.79 (1.16) | 93.67 (1.60) | 97.30 (1.91) | 105.47 (2.81) |
| 10 cN/1 min (n=9) | 215 213 (8955) | 40.9 [57.7] | 33.1 [58.6] | 25.9 [60.0] | 103.69 (0.66) | 98.90 (0.90) | 104.27 (1.20) | 110.48 (1.48) |
| 10 cN/6 min (n=5) | 195 629 (3623) | 40.7 [58.3] | 33.2 [59.1] | 26.0 [57.7] | 107.57 (0.96) | 103.69 (1.39) | 108.99 (1.68) | 111.82 (2.07) |
| 10 cN/15 min (n=4) | 165 443 (1691) | 39.8 [46.0] | 31.6 [51.2] | 28.6 [49.1] | 96.56 (1.09) | 89.99 (1.57) | 101.53 (2.06) | 100.20 (2.09) |
| 10 cN/30 min (n=5) | 153 562 (10 438) | 39.5 [29.1] | 35.2 [32.4] | 25.3 [31.5] | 76.71 (0.90) | 73.49 (1.42) | 76.99 (1.45) | 81.37 (1.92) |
| 15 cN/1 min (n=11) | 186 650 (10 240) | 38.9 [53.4] | 33.8 [51.2] | 27.2 [58.9] | 101.58 (0.66) | 97.30 (0.95) | 99.56 (1.13) | 110.18 (1.41) |
| 15 cN/6 min (n=6) | 169 086 (8336) | 39.3 [36.4] | 32.6 [42.8] | 28.1 [51.2] | 90.09 (0.88) | 82.34 (1.20) | 91.14 (1.60) | 99.77 (1.87) |
| 15 cN/15 min (n=4) | 135 465 (9011) | 38.8 [17.1] | 31.1 [20.1] | 30.0 [29.5] | 69.02 (0.88) | 65.10 (1.36) | 68.64 (1.59) | 74.49 (1.65) |
| 20 cN/6 min (n=6) | 139 252 (7688) | 38.0 [14.4] | 33.8 [15.7] | 28.2 [18.2] | 61.94 (0.56) | 60.25 (0.94) | 61.62 (0.92) | 64.61 (1.06) |
| 30 cN/1 s (n=6) | 151 479 (13 079) | 38.2 [38.7] | 33.5 [41.3] | 28.3 [43.4] | 82.13 (0.74) | 80.16 (1.19) | 83.07 (1.33) | 83.71 (1.37) |