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Cytotoxic effect of various concentrations of 5-FC (A), 5-FU (B), and induction of cytosine deaminase (AxCACD) (C) on rabbit Tenon's capsule fibroblast growth at different incubation times. 5-FC does not affect cell growth (A), although 5-FU inhibits cell growth in a time dependent and dose dependent manner (B). Infection of AxCACD did not produce a cytotoxic effect (C). Each point represents mean (SD). (***p <0.001, ANOVA) MOI = multiplicity of infection.
