Figure 4.

Cytotoxic effects and reversibility of 1000 μg/ml of 5-FC and cytosine deaminase induction at MOI 10 on rabbit Tenon's capsule fibroblast growth at different incubation times. 5-FC was removed at day 3, 6, or 9. Cell viability was reversed after some period since 5-FC was removed. Each point represents mean (SD). (***p <0.001, ANOVA) Data under the asterisks showed significant difference compared to the control as the asterisks indicated. After 5-FC removal, the data were also compared to the toxic control without 5-FC removal (++p <0.01, +++p <0.001, ANOVA).