Table 1.

Clinical criteria for stromal herpetic keratitis or keratouveitis caused by herpes simplex or varicella zoster virus (group 1) and non-herpetic keratitis (group 2)

Stromal herpetic keratitis and keratouveitis (group 1) (the diagnosis was made if at least five of the criteria were satisfied, one had to be the exclusion of systemic granulomatous disease)
• Exclusion of systemic granulomatous disease
• Documented recurrent stromal keratitis
• Interstitial keratitis with deep stromal vascularisation or acute stromal necrosis
• Sector granulomatous iritis, iris stroma haemorrhage, or sector atrophy of the iris
• History of dendritic keratitis
• Documented stromal disciform keratitis with endothelial precipitates
• Marked corneal hypoaesthesia
• Secondary glaucoma
• Documented response to combined systemic aciclovir and local steroid treatment
Non-herpetic keratitis and keratouveitis (group 2) (inflammatory corneal disease with no evidence of herpetic keratitis, that is)
• Interstitial keratitis without a history of recurrent inflammatory episodes
• Viral keratitis of known other origin (varicella zoster, adenovirus)
• Keratitis associated with systemic rheumatic or autoimmune disease
• Bacterial or mycotic keratitis without recurrence