Table 2.
Standard early postoperative treatment (group 1 and 2) | Daily dose | Duration of treatment |
Prednisolone acetate (2.5%) | three times | first 7 days |
Prednisolone acetate (1.0%) | three times | from day 7, until the removal of the last sutures (>1 year after surgery) |
Atropine (1%) | once | first 7 days |
Gentamicin (0.3%) or tobramycin (0.5%) | three times | until closure of the corneal epithelium |
Postoperative antiviral prophylaxis (group 1) | ||
Indication for surgery | Daily dose by mouth* | Duration of treatment |
*Maximum dose; modifications necessitated by differences in renal function and body weight were as recommended by the manufacturer. | ||
(aciclovir) | ||
Active herpetic keratouveitis and herpetic stromal keratitis | 5 × 800 mg | 2–4 weeks |
3 × 400 mg | 2–12 months | |
Herpetic ulcerate stromal keratitis; no activity, recurrence free <1 year | 3 × 800 mg | 4–8 weeks |
3 × 400 mg | 2–12 months | |
Herpetic corneal scars; no activity; recurrence free <3 years | 3 × 400 mg | 3 months |