Table 2.
Protocol for antimetabolite use and risk factor for failure scoring. (Based on protocol developed by Professor RN Weinreb, Shiley Eye Centre, San Diego)
| Risk factors for failure | Score |
| Race: | |
| Indian, Asian | 3 |
| Afro-Caribbean | 5 |
| Combined cataract and glaucoma surgery | 5 |
| Previous ocular surgery | 5 |
| Secondary glaucoma (uveitis, neovascular) | 5 |
| Topical treatments >2 | 3 |
| Duration of topical treatment >1 year | 3 |
| IOP target <16 mm Hg | 3 |
| Conjunctival cicatrising disease | 5 |
| Age <20 years | 5 |
| Age <40 years | 3 |
| Diabetes | 1 |
| Previous ALT | 1 |
If score: give:
Less than 5: no antimetabolites
Between 6–10: 5-FU (25 mg/ml)
Between 11–15: MMC 0.2 mg/ml
Over 15: MMC 0.4 mg/ml.