Figure 5.

Intracellular immunolocalisation of Smad4 in lens epithelial cells following cataract surgery. (A) (Case 1), epithelial cells (arrows) in an uninjured lens show Smad4 immunoreactivity in the cytoplasm. In (B) a specimen obtained 6 days after cataract surgery (case 5), some of lens epithelial cells show Smad4 in the nuclei (arrowheads), while others do not. (C) Nuclei of the lens epithelial cells (arrowheads) in the closed capsular bag 1 year postoperatively exhibit nuclear Smad4 immunoreactivity (case 10). AC = anterior capsule. Indirect immunostaining. Bar, 20 μm (A) and (B), and 50 μm (C).