Table 1.
Case | Age | Sex | Symptoms | Worst time or condition | History of subconjunctival bleeding | BUT | FCT | DTC | Reflex tearing | FL | RB | MGD-LTD |
Group A | ||||||||||||
1 | 32 | M | Dryness | PM | No | 4 | 2 | Absent | Present | Positive | Negative | Absent |
2 | 32 | M | Dryness | PM | No | 2 | 1 | Present | Present | Negative | Negative | Absent |
3 | 36 | M | Dryness | PM | No | 2 | 2 | Absent | Present | Negative | Positive | Absent |
4 | 31 | F | Dryness | PM | No | 3 | 1 | Present | Present | Positive | Positive | Absent |
5 | 31 | F | Dryness | PM | No | 3 | 1 | Absent | Present | Negative | Positive | Absent |
Mean (SD) | 32.4 (2.6) | 2.8 (0.8) | 1.5 (0.5) | |||||||||
Group B | ||||||||||||
6 | 61 | F | Dryness | PM, reading | Yes | 3 | 2 | Present | Absent | Positive | Positive | Present |
7 | 82 | F | Blurry vision | AM, reading | Yes | 1 | 3 | Present | Present | Positive | Positive | Present |
8 | 73 | M | Blurry vision, burning sensation | AM, reading | No | 2 | 3 | Present | Present | Positive | Positive | Present |
9 | 59 | F | Blurry vision, burning sensation | AM, reading | No | 0 | 1 | Present | Absent | Positive | Positive | Present |
10 | 65 | M | Blurry vision | PM, reading | Yes | 0 | 3 | Present | Present | Positive | Positive | Present |
11 | 53 | F | Blurry vision | AM, reading | No | 2 | 2 | Present | Present | Positive | Positive | Present |
12 | 64 | M | Blurry vision | AM, reading | Yes | 0 | 2 | Present | Absent | Positive | Positive | Present |
13 | 71 | F | Pain, dryness | AM, reading | Yes | 2 | 2 | Present | Present | Positive | Positive | Present |
Mean (SD) | 66 (9.1) | 1.2 (1.1) | 2.2 (0.7) | |||||||||
Group C | ||||||||||||
14 | 59 | M | Dryness | PM, reading | Yes | 2 | 5 | Present | Present | Positive | Positive | Present |
15 | 52 | F | Pain, light sensitivity | PM, light, wind/ reading | Yes | 0 | 8 | Present | Present | Positive | Positive | Present |
16 | 67 | F | Pain | PM, reading | Yes | 2 | 6 | Present | Present | Positive | Positive | Present |
17 | 75 | F | Pain | PM, reading | Yes | 2 | 5 | Present | Present | Positive | Positive | Present |
18 | 63 | F | Pain | PM, reading | No | 2 | 10 | Present | Present | Positive | Positive | Present |
19 | 79 | F | Pain, dryness | AM, reading | Yes | 1 | 7 | Present | Present | Positive | Positive | Present |
20 | 57 | M | Pain, dryness | AM, reading | No | 2 | 8 | Present | Present | Positive | Positive | Present |
21 | 60 | F | Pain, dryness | PM, reading | Yes | 3 | 15 | Present | Present | Positive | Positive | Present |
Mean (SD) | 64 (9.1) | 1.7 (0.8) | 8 (3.2) |
FCT = fluorescein clearance test measuring the average wetting length (mm) for 1 min with Schirmer strip (with anaesthetic) at 10 and 20 min time points. Reflex = reflex tearing determined by nasal stimulation performed at the 30 min time point (present: wetting length (mm) greater than the above baseline value; absent: wetting length equal to or no greater than the baseline value). DTC = delayed tear clearance measured by FCT (absent: no DTC and is found in normal subjects when dye cleared within 20 min; present: dye clearance was delayed more than 20 min). BUT = tear break up time (seconds). MGD = meibomian gland dysfunction determined by meibum expression (absent: meibum was readily expressed; present: meibum poorly or not expressed by digital compression). PM = as the day progresses; AM = upon awakening; F = female; m = male; FL = fluorescein; RB = rose bengal.