Table 1.
Reported outcomes with alternative therapies for uveal melanoma (comparative studies)
| Author | Year | Study groups | Outcome | Rate* | |
| Adams24 | 1988 | Enucleation | 5 year tumour related mortality | 0.77–1.07 | |
| Plaque | (rate ratio) | ||||
| Seddon28 | 1990 | Enucleation | 5 year survival rate | 68% | |
| Proton beam | 81% | ||||
| Augsburger30 | 1990 | Plaque | Actuarial 5 year survival | 82% | |
| Resection | probability | 85% | |||
| Foulds8 | 1991 | Enucleation | Melanoma related mortality | 70% | |
| Resection | 76% | ||||
| Kroll29 | 1998 | Plaque | 5 year all cause mortality | 23% | |
| Helium ion | 26% | ||||
| Augsburger25 | 1999 | Enucleation | Cumulative 15 year survival | 57% | |
| Plaque | 62% | ||||
| COMS26 | 2001 | Enucleation | 5 year all cause mortality | 19% | |
| Plaque | 18% | ||||
| COMS33 | 1998 | Enucleation ± radiation | 5 year all-cause survival | 57%–62% | |
| Puusaari27 | 2003 | Plaque | 5 year all-cause survival | 62% | |
COMS, Collaborative Ocular Melanoma Study.
*Difference not statistically significant in any study.