Table 3.

 Treatment and outcome of patients according to risk factors detected on histopathological examination

Feature	Adjuvant treatment	Events
Isolated choroidal invasion (n = 55)	None	Orbital relapse = 1; orbital and systemic relapse = 2
Isolated post-laminar optic nerve (n = 25)	Chemotherapy = 4; none = 21	None
Post-laminar optic nerve with major choroidal invasion (n = 6)	Chemotherapy = 2	None
	None = 4	Orbital and systemic relapse = 1; orbital relapse = 1
Post-laminar optic nerve invasion with scleral invasion (n = 5)	Chemotherapy = 5	CNS relapse = 1; CNS and systemic relapse = 2
Cut end invasion (n = 10)	Chemotherapy and orbital radiotherapy = 10	None
Isolated scleral invasion (n = 5)	None = 2	Orbital relapse = 1
	Chemotherapy = 3	Systemic relapse = 1
Isolated anterior chamber invasion (n = 2)	None	None

Isolated choroidal and isolated scleral invasion includes patients with less than post-laminar optic nerve involvement. Isolated post-laminar optic nerve disease includes patients with no scleral invasion or focal choroidal invasion. Isolated anterior chamber invasion included no concomitant choroidal, scleral, or post-laminar optic nerve disease.