Table 1.

 Characterisation of retinal vasculature in the transgenic mouse lines

Retinal vasculature characteristics	Line 029	Line 050/056	Line 094
Capillary non-perfusion	+	+	+
Microaneurysms	+	+	+
Venous dilatation	–	+	+
Tortuosity of blood vessels	+	–	+
Haemorrhages	±	++	++
Neovascularisation	+	++	++
Preretinal haemorrhage	–	+	++
Vitreous haemorrhage	–	+	++
Fibrovascular proliferation	–	+	+
Cataracts*	–	+++	+
Retinal detachment	–	+++	++

*Other pathological features observed through clinical and histological examinations.