Table 5.
Association (R2) between sources of variability and intraobserver/intravisit rim area differences (mm2)
| Source of variability | HRT Classic | HRT Explorer | HRT-II Explorer | |||
| R2 | p Value | R2 | p Value | R2 | p Value | |
| Reference height difference | 0.7 | <0.0001 | 0.7 | <0.0001 | 0.5 | <0.0001 |
| Mean MPHSD | 0.5 | <0.0001 | 0.4 | <0.0001 | 0.5 | <0.0001 |
| Central nuclear dip | 0.1 | 0.005 | 0.3 | <0.0001 | 0.2 | <0.0001 |
| LOCS III nuclear opalescence | 0.1 | 0.001 | 0.2 | 0.0006 | 0.2 | <0.0001 |
| LOCS III nuclear colour | 0.03 | 0.1 | 0.1 | 0.001 | 0.2 | <0.0001 |
| Cylindrical power | 0.2 | <0.0001 | 0.03 | 0.4 | 0.1 | 0.005 |
| Spherical power | 0.07 | 0.02 | 0.02 | 0.2 | 0.04 | 0.1 |
| Spherical equivalent | 0.04 | 0.08 | 0.01 | 0.3 | 0.02 | 0.2 |
| Age | 0.05 | 0.05 | 0.04 | 0.1 | 0.07 | 0.02 |
| Baseline rim area | 0.05 | 0.05 | 0.02 | 0.2 | 0.0003 | 0.9 |
| Disc area | 0.001 | 0.8 | 0.01 | 0.5 | 0.001 | 0.8 |
| Intraocular pressure | 0.05 | 0.05 | 0.05 | 0.07 | 0.01 | 0.4 |
| LOCS III posterior subcapsular | 0.01 | 0.4 | 0.001 | 0.8 | 0.005 | 0.6 |
| LOCS III cortical | 0.0001 | 0.9 | 0.005 | 0.6 | 0.01 | 0.5 |
MPHSD = mean pixel height standard deviation, LOCS III = Lens Opacity Classification System III.