Figure 4.

Effect of hyperthermia and β adrenergic stimulation on caerulein induced intrapancreatic trypsinogen activation: pancreatitis was induced in rats after prior stress induced by hyperthermia (A) or administration of isoproterenol (B), as described in the text. Trypsinogen activation was monitored either by quantitation of trypsin activity or by measurement of trypsinogen activation peptide (TAP), as described in the text. Results are expressed as a per cent of the increase noted in non-stressed animals given caerulein (that is, maximal increase). Results represent mean (SEM) values for at least three animals at each time point. *Significantly different (p<0.05) from non-stressed caerulein treated rats.