Figure 6.

(A) Helicobacter pylori (10⁷ cfu) did not increase carbachol (0.1–10 μM) stimulated pepsinogen secretion from dispersed human peptic cells. The effects of carbachol on basal pepsinogen secretion were statistically significant with respect to control experiments (†p<0.05). Results are presented as mean (SEM) of six separate experiments. Basal secretion=6.6 (0.6)%. The H pylori strains used in these experiments correspond to strains HP33, HP34, HP42, HP43, and HP46. (B) H pylori (10⁷ cfu) did not affect cholecystokinin octapeptide (CCK-OP 1 μM) stimulated pepsinogen secretion. The effect of CCK-OP on basal secretion was also significant (†p<0.05). Results are presented as mean (SEM) of six separate experiments. Basal secretion=5.9 (0.2)%. The H pylori strains used in these experiments correspond to strains HP50, HP52, and HP58.