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Cell preincubation with Nw-monomethyl-l-arginine (l-NMMA) (a nitric oxide synthase inhibitor) significatively inhibited both carbachol and Helicobacter pylori stimulated pepsinogen secretion from dispersed human peptic cells (*p<0.05; **p<0.01). Results are presented as mean (SEM) of 5–9 separate experiments. Basal secretion=6 (0.2)%. The H pylori strains used in these experiments correspond to strains HP25, HP31, HP32, HP33, and HP34.
