Table 2.

Sex related differences in the human mucosal glutathione (GSH) system in the antrum and duodenum†

GSH parameter	Males (n=104)	Females (n=98)
GSH content (nmol/mg protein)
Antrum	21.2 (0.8)	24.8 (1.0)**
Duodenum	34.2 (1.4)	36.2 (1.2)
GST activity (nmol/min/mg protein)
Antrum	576 (21)	679 (32)**
Duodenum	813 (30)	851 (33)
GSTA content (μg/mg protein)
Antrum	4.2 (0.5)	4.8 (0.7)
Duodenum	20.4 (1.0)	19.5 (1.0)
GSTP content (μg/mg protein)
Antrum	15.3 (0.9)	17.7 (1.1)
Duodenum	11.3 (0.7)	11.1 (0.7)

Values are mean (SEM).

†Matched for endoscopic diagnosis.

**Significantly different from antral value in males, p<0.01.

GST, glutathione S-transferase; GSTA, glutathione S-transferase alpha; GSTP, glutathione S-transferase pi.