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Effect of propranolol on the maximal change in short circuit current (Isc) induced by histamine with or without exposure to tumour necrosis factor α (TNF-α). Cells were incubated with 100 μM propranolol (prop) 10 minutes prior to addition of histamine (hist). Data are presented as means (SEM) from 3–4 monolayers. Cells were exposed to TNF-α for 5–24 hours. Statistical significance of the differences in change in Isc was evaluated using the non-parametric Mann-Whitney test: *p<0.05.
