Figure 1.
Change in seroprevalence of Helicobacter pylori carriage between 1973 and 1994 by age and cagA status (defined by CagA seropositivity). Both H pylori and cagA status were determined, and the 911 study subjects were stratified by age (14–44 and ≥45 years). Data are shown for specimens obtained in 1973 (n=408) and 1994 (n=503). The decline in seroprevalence of H pylori cagA+ strains in subjects 14–44 years old was significantly (p<0.001) greater than that for H pylori cagA− strains.