Table 3.

Duodenal effects of photodynamic therapy (PDT). Endoscopic findings are shown prior to PDT, in the first six weeks after PDT, and at longer follow up times, together with any intervention required for stenosis or haemorrhage

		Early effects (up to 6 weeks)				Late effects
Patient No	Endoscopy pre 1st PDT	Endoscopy	Symptoms	Treatment	Time after 1st PDT	Endoscopy	Symptoms	Treatment
1	Normal	Normal	—	—	—	—	—	—
2	Normal	Duodenal necrosis (small area)	—	—	—	—	—	—
3	Normal	Duodenal necrosis	(A) Bleeding	Embolisation	—	—	—	—
			(B) Obstruction	duodenal stent
4	Stenosed	(A) Duodenal stent before PDT	—	—	2 months	Tumour ingrowth in stent	Obstruction	2nd duodenal stent
		(B) Duodenal stent in situ	—	—	—	—	—	—
5	Ulcerated ampulla	More extensive ulceration, duodenal stenosis	—	—	—	—	—	—
6	Normal	Duodenal necrosis	Bleeding	Endoscopic injection	—	—	—	—
7	Normal	Normal	—	—	—	—	—	—
8	Ulcerated ampullary tumour	n/a	—	—	(A) 10 months	Stenosis	Obstruction	Duodenal stent
					(B) 26 months	Tumour ingrowth	Obstruction	2nd duodenal stent
9	Normal	Duodenal necrosis. CBD—duodenal fistula	—	Biliary stent	—	—	—	—
10	Ulcerated duodenum and ampulla	CBD—duodenal fistula	—	Biliary stent	5 months	Stenosis	Obstruction	Duodenal stent
11	Ampullary tumour	Necrosis around stent	—	—	—	—	—	—
12	Normal	Duodenal necrosis (small area)	—	—	16 months	Stenosis	—	—
13	Normal	Necrosis around ampulla. Stenosis	—	—	3 months	Stenosis	—	—
14	Normal	(A) Duodenal necrosis	—	—	13 months (3 months after last PDT)	Tumour in duodenal wall	Bleeding	Transfusion
		(B) CBD—duodenal fistula
		(C) Further duodenal necrosis
15	Normal	Normal	—	—	14 months	Stenosis	Obstruction	Duodenal stent
16	Haemorrhagic, distorted duodenum	Ulcerated duodenum	Obstruction	Duodenal stent	4 months	Stenosis	Obstruction	Gastroenterostomy

n/a, data not available; CBD, common bile duct