Figure 4.
Blunting effect of butyrate (NaB) on Cdx2 downregulation by oncogenic Ras. Control Caco2-H and Ras activated Caco2-T cells were transfected with the pCdx2-1Luc and pCMV-βGal plasmids and treated for 48 hours with 2 mM NaB or vehicle alone. Luciferase activity was related to β-galactosidase and the results are expressed as arbitrary units of luciferase activity. The results are means of three independent experiments.