Table 2.
Baseline characteristics of hepatocellular carcinoma in Toronto in 257 patients
Variable | No (%) (n=257) |
Mean age (y) | 60.1 (12.5) |
Median age (y) | 63 |
Sex male | 188 (73.1) |
Country of origin | (missing data 4) |
South-East Asia | 123 (48.6) |
Canada | 44 (17.3) |
Europe south | 33 (13.0) |
Other | 53 (20.1) |
Main risk factors | (missing data 6) |
HBV | 147 (58.5) |
HCV | 54 (21.5) |
Alcohol | 39 (15.5) |
Diagnosis | |
Biopsy or surgical specimen | 173 (67.3) |
Clinical/radiological+AFP >400 ng/ml | 49 (19.1) |
Clinical/radiological | 35 (13.6) |
Symptoms | (missing data 21) |
Asymptomatic patients. | 122 (51.7) |
Symptomatic patients (before diagnosis) | 114 (48.3) |
Constitutional symptoms* | 82/122 (67.2) |
Abdominal symptoms* | 65/114 (57.0) |
Non-tumorous liver | (missing data 13) |
Cirrhosis | 178 (73.0) |
Chronic hepatitis | 59 (24.2) |
Normal liver | 7 (2.8) |
AFP levels | |
>400 ng/ml | 105 (40.8) |
11–400 ng/ml | 92 (35.8) |
≤10 ng/ml | 60 (23.4) |
Tumour type | |
Unifocal | 107 (41.6) |
Multifocal | 75 (29.2) |
Diffuse massive | 75 (29.2) |
Vascular macroscopic invasion | 43 (16.7) |
Metastasis at diagnosis | 15 (5.8) |
Treatments* | |
Resection/transplantation/alcohol | 72/0/23 (37.0) |
Chemoembolisation and experimental | 29 (11.3) |
Palliative, Chinese herbal, tamoxiphen | 133 (51.7) |
*More than 100% due to multiple symptoms in some patients.
HBV, hepatitis B virus; HCV, hepatitis C virus; AFP, alpha fetoprotein.