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. 2002 Aug;51(2):248–252. doi: 10.1136/gut.51.2.248

Table 3.

Comparison of recipients who experienced graft fibrosis at a fast (greater than 0.8 fibrosis units per year) or slow (less than 0.8 units per year) rate

Slow fibrosis (<0.8 units/year) Fast fibrosis (>0.8 units/year) Univariate analysis Multivariate analysis
n 29 27
Recipient age (y) 50 (34–67) 46 (28–65) 0.3 0.7
Recipient sex (M/F) 24/5 21/6 0.6 0.8
Caucasian 15 14 0.4 0.5
Cyclosporin/tacrolimus 26/3 23/4 0.6 0.4
Treated rejection 10 11 0.6 0.12
>1 episode rejection 3 0 0.2 0.8
HBsAg positive* 3 2 0.7 0.5
Cold ischaemic time (min) 787 (261–1280) 780 (353–1055) 0.7 0.4
Warm ischaemic time (min) 44 (25–58) 51 (33–76) 0.02 0.01
Donor sex (M/F) 18/11 20/7 0.34 0.34
Donor age (y) 38 (15–64) 45 (17–67) 0.09 0.02
Date of transplantation (pre/post 11/96) 16/13 12/15 0.42 0.96

HBsAg, hepatitis B virus surface antigen.

*Serum status pre-transplant—all were serum HBsAg negative post-transplant.

Data are median (range).