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. 2002 Sep;51(3):329–335. doi: 10.1136/gut.51.3.329

Table 2.

Relative risk reduction (RRR), absolute risk reduction (ARR), and number needed to treat (NNT) with respect to ulcer and/or therapy requiring dyspepsia

RRR (%) (95% CI) ARR (%) (95% CI) NNT (n) (95% CI)
Ulcer
    OAC-P 79 (4.5–95) 4.6 (0.7–8.5) 22 (12–143)
    OAC-O 80 (11.1–96) 4.7 (0.8–8.6) 21 (12–125)
    O-O 100 5.8 (2.1–9.5) 17 (11–48)
Therapy requiring dyspepsia
    OAC-P 47 (8.8–69) 9.3 (1.7–17) 11 (6–59)
    OAC-O 48 (11–69) 9.5 (2.0–17) 11 (6–50)
    O-O 38 (-3.5–63) 7.6 (-0.3–16) 13 (6–∞)

OAC-P, one week treatment with omeprazole, amoxicillin, and clarithromycin, followed by four weeks of placebo; OAC-O, one week treatment with omeprazole, amoxicillin, and clarithromycin, followed by four weeks of omeprazole; O-O, five week treatment with omeprazole.