Table 1.

Appearance of gross bleeding in mice (%) during dextran sodium sulphate treatment.

	Homozygous transgenic	Heterozygous transgenic	Wild-type
Day 0	0 (n=36); NS	0 (n=38); NS	0 (n=30)
Day 1	0 (n=36); NS	0 (n=38); NS	0 (n=30)
Day 2	6 (n=36); NS	0 (n=38); NS	0 (n=30)
Day 3	25 (n=36);**	3 (n=38); NS	0 (n=30)
Day 4	80 (n=35);***	19 (n=38); NS	6 (n=30)
Day 5	100 (n=17);***	61 (n=19); NS	38 (n=15)
Day 6	100 (n=17);***	78 (n=19);*	50 (n=15)
Day 7	100 (n=5); NS	100 (n=19);*	75 (n=15)
Day 8	ND (n=0)	100 (n=13); NS	100 (n=10)

Significance was calculated using a χ² test. All values were compared with wild-type mice: *p<0.05, **p<0.01, ***p<0.001.