Figure 5.
Complement receptor type 1 (CR1) gene polymorphism dependent binding of immune complexes (IC) to erythrocytes. Hepatitis B virus (HBV) DNA (A) and hepatitis C virus (HCV) RNA (B) bound to erythrocytes were quantified by real time detection polymerase chain reaction and box plots of the viral gene levels for each polymorphism are shown. Boxes and bars are as in fig 1 ▶. The genotypes are: HH, individuals homozygous for the CR1 high density allele; HL, individuals heterozygous for the CR1 gene polymorphism; LL, individuals homozygous for the CR1 low density allele. (A) *p=0.021, **p=0.007; (B) *p=0.008, **p=0.001.