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. 2003 Jan;52(1):79–83. doi: 10.1136/gut.52.1.79

Figure 3.

Figure 3

Pathological and apoptotic indices of ulcerative colitis-like lesions caused in the colorectum by F varium culture supernatant or butyric acid enemas. The mean pathological index of mice treated with F varium (3.3) or butyric acid (3.5) was higher than that of mice treated with HCl (p=0.021 and 0.019), ABCM broth (both p<0.001), or phosphate buffered saline (PBS) (both p<0.001). Similarly, the mean apoptotic indices for mice treated with F varium (24.0%) or butyric acid (20.8%) were higher than for HCl (p=0.0045 and 0.012), ABCM broth (both p<0.001), or PBS (both p<0.001). The mean apoptotic index of mice treated with HCl (10.1%) was higher than that of ABCM broth or PBS (both p<0.001). Values are mean (SD); statistical analyses were performed using the Mann-Whitney U test with Bonferroni’s correction.