Table 5.

Demographic features of patients with two or more liver biopsies

	No treatment between biopsies 1 and 2	Treated between biopsies 1 and 2	p Value
No of patients (%)
Male	58 (62.4)	26 (57.8)
Female	35 (37.6)	19 (42.2)	0.33*
Age at infection	25.8 (10.3)	29.8 (11.6)	0.112†
Age at biopsy	43.1 (10.84)	45.55 (9.83)	0.218†
Necroinflammatory score (Ishak) bx1	3.04 (1.92)	4.09 (1.76)	0.003†
Fibrosis score bx1
Ishak	1.94 (1.82)	2.89 (1.86)	0.005†
METAVIR	1.24 (1.27)	1.86 (1.4)	0.02†
Duration infection to 1st biopsy (y)	15.6 (7.3)	16.9 (8.19)	0.464†
Duration 1st biopsy to 2nd biopsy	2.73 (1.38)	2.67 (1.24)	0.801†
Rate infection to 1st biopsy (fibrosis units/y)
Ishak	0.15	0.22 (0.23)	0.177†
METAVIR	0.096	0.12 (0.16)	0.218†
Risk factors (%)
Blood	19 (20.4)	14 (31.1)
IVDU	29 (31.2)	18 (40)	0.133*
Unknown	45 (48.4)	13 (28.9)
Alcohol consumption (units/week) (%)
Unknown	35 (37.6)	17 (37.8)
<40	46 (49.6)	17 (37.8)	0.189*
>40	12 (12.9)	11 (24.4)
Caucasian	70 (75.3)	34 (75.6)	0.971*
Non-Caucasian	23 (24.7)	11 (24.4)
Viral genotype (%)
1	25 (26.9)	12 (26.7)
Non-1	16 (17.2)	10 (22.2)	0.765*
Unknown	52 (55.9)	23 (51.1)

Values are mean (SD) or number (%). …IVDU, intravenous drug use. … *χ² test

†Independent t test.