Table 2.
Effect of treatment with infliximab or placebo
| Week 0 | Week 6 | Improvement | ||||
| Group | Placebo (n=20) | Infliximab (n=23) | Placebo | Infliximab | Placebo | Infliximab |
| Prednisolone equivalent (mg/day) | 28 (7) | 32 (11) | 14 (10) | 13 (12) | 14 (12) | 19(15) |
| C reactive protein | 12 (10) | 9 (9) | 13 (14) | 9 (8) | −1 (10) | 0 (10) |
| UC severity score | 8.5 (2) | 8 (2) | 5 (3) | 5 (3) | 4 (3) | 4 (3) |
| Baron score | 2.4 (0.5) | 2 (0.5) | 1 (1) | 1 (1) | 1 (1) | 1 (1) |
| IBDQ | 114 (29) | 127 (40) | 139 (43) | 163 (40) | 25 (28) | 36 (49) |
| EuroQol | 49 (17) | 52 (16) | 54 (23) | 59 (19) | 4 (16) | 7 (17) |
Data are shown as means (standard deviation). Glucocorticoid doses have been converted to prednisolone equivalents for those patients receiving 6- methyl prednisolone.
UC, ulcerative colitis; QOL, quality of life; IBDQ, QOL index for inflammatory bowel disease.