Table 9.

Concentrations (mM) of hepatic phosphorylated metabolites in control rats and rats with chronic cholestatic liver disease following common bile duct ligation

Time	PME	Pi	PDE	ATP
Baseline	3.05 (0.24)	1.64 (0.11)	0.94 (0.15)	3.13 (0.22)
12 days	3.21 (0.19)	1.56 (0.10)	1.01 (0.07)	2.69 (0.22)
27 days	3.20 (0.28)	1.72 (0.16)	0.98 (0.09)	2.60 (0.30)
46 days	2.64 (0.30)	1.43 (0.17)	0.97 (0.19)	1.66 (0.13)*
Age matched controls	3.04 (0.13)	1.30 (0.03)	1.49 (0.37)	3.28 (0.34)

Values are means (SEM).

PME, phosphomonoesters; Pi, inorganic phosphate; PDE, phosphodiesters; ATP, adenosine triphosphate.

*p<0.05 versus baseline, aged matched controls, 12 day, and 27 day cholestatic rats.