Table 1.
Case No | Sex | Age of CD Dx (y) | Age of neoplasia Dx (y) | Type of neoplasia | Location | Presentation | Diagnostic study |
1 | M | 49 | 53 | Adenoma | Duodenum | Asymptomatic | OGD* |
2 | F | 44 | 83 | Adenoma | Duodenum | Asymptomatic | OGD* |
3 | M | 16 | 53 | Adenoma | Duodenum | Asymptomatic | OGD* |
4 | M | 31† | 21 | Adenocarcinoma | Ileum | Acute abdomen | Exploratory laparotomy |
5 | M | Infant †‡ | 55 | Adenocarcinoma | Jejunum | Acute abdomen | Exploratory laparotomy |
6 | F | 70 | 70 | Adenocarcinoma | Jejunum | Iron deficiency anaemia | Abdominal CT enteroscopy |
7 | M | Infant ‡ | 55 | Adenoma; adenocarcinoma | Jejunum | Iron deficiency anaemia | UGI/SI enteroscopy |
CD, coeliac disease; Dx, diagnosis; UGI/SI, upper gastrointestinal series with small intestinal series; OGD, oesophagogastroduodenoscopy; CT, computed tomography.
*OGD performed to check the status of coeliac disease.
†Coeliac disease diagnosed after pathology slides from small bowel adenocarcinoma resection were reviewed.
‡Originally diagnosed in infancy but were told they “grew out of it.” Therefore, had been exposed to gluten >50 years; subsequently re-diagnosed with coeliac disease as adults.