Table 1.
Expression of transforming growth factor β-1 (TGFβ) and its receptors TGFβR I and TGFβR II in human neuroendocrine tumours (NET)
| TGFβ | TGFβR I | TGFβR II | |||||||||
| Patient No | Sex | NET | Tumour origin | Synaptophysin | T | M | T | M | T | M | Ki-67 (%) |
| 1 | M | Foregut | Pancreas | + | − | + | + | − | + | − | <1 |
| 2 | F | Foregut | Jejunum | + | + | + | + | + | + | + | <1 |
| 3 | M | Foregut | Pancreas | + | + | − | + | + | + | + | <1 |
| 4 | M | Foregut | Pancreas | + | + | − | + | − | + | − | 5 |
| 5 | F | Foregut | Pancreas | + | + | + | + | + | + | + | na |
| 6 | M | Midgut | Caecum | + | − | + | + | − | + | − | 10 |
| 7 | M | Midgut | Caecum | + | + | + | + | + | + | + | 5 |
| 8 | F | Midgut | Appendix | + | − | + | + | − | + | − | <1 |
| 9 | M | Midgut | Caecum | + | + | + | + | − | + | − | 5 |
| 10 | M | Hindgut | Sigma | + | − | − | + | − | + | − | 70 |
| 11 | M | Hindgut | Sigma | + | + | − | + | + | + | + | 40 |
| 12 | M | Hindgut | Rectum | + | + | + | + | + | + | − | 80 |
+, positive signal; −, no signal; T, tumour; M, mesenchyme; na, not available.
Ki-67 proliferation index, as detected by immunohistochemistry.