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. 2003 Nov;52(11):1591–1597. doi: 10.1136/gut.52.11.1591

Figure 4.

Figure 4

Expression of NOD2 in colon from Crohn’s disease (CD) patients and controls. (A, B) Uninvolved colon from a CD patient stained with 2D9 (A) or with isotype matched control antibody (B). (C) Inflamed colon from a CD patient showing no detectable 2D9 staining in the colonic epithelium. (D) Distal colon from a CD patient with Paneth cell metaplasia (indicated by arrowheads) stained with 2D9. (E) Inflamed colon from a CD patient showing focal NOD2 staining in colonic epithelium. (F) Inflamed colon from an ulcerative colitis patient showing focal NOD2 staining in colonic epithelium (indicated by arrowheads). (G–I) High power views of (D), (E), and (F), respectively. Magnification: 500× (A–F); 2500× (G–I).