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. 2003 Dec;52(12):1756–1763. doi: 10.1136/gut.52.12.1756

Table 6.

Recurrences overall and by stage (I, II, and III) compared with the status of BRCA1 loss of heterozygosity (LOH)

Informative cases (%) With LOH (%) Without LOH (%) p Value
Overall recurrences
    Yes 51 (23.8) 31 (60.8) 20 (39.2) 0.0003
    No 163 (76.2) 53 (32.5) 110 (67.5)
Stage I
    Yes 5 (17.2) 5 (100) 0 0.008
    No 24 (82.8) 6 (25) 18 (7.5)
Stage II
    Yes 14 (14.6) 10 (71.4) 4 (28.6) 0.01
    No 82 (85.4) 26 (31.7) 56 (68.3)
Stage III
    Yes 32 (36) 16 (50) 16 (50) 0.32
    No 57 (64) 21 (36.8) 36 (73.2)