Table 1.

Intestinal tissue specimens included in the study

Age (y)	Sex	Diagnosis	CD duration (y)	Surgical procedure	B/T
Control group
70	F	Right colon cancer		Right hemicolectomy	—/C
62	M	Right colon adenocarcinoma		Right hemicolectomy	—/C
55	M	Small intestine carcinoma		Ileum resection	—/I
77	F	Right colon cancer		Right colectomy	—/C
79	M	Right colon adenocarcinoma		Right hemicolectomy	—/C
78	F	Right colon cancer		Right hemicolectomy	—/C
51	M	Colorectal cancer		Proctocolectomy	—/C
CD group
48	F	CD, fistulas	3	Ileocaecal resection	B3/O
42	F	CD, bowel obstruction	3	Ileocaecal resection	B2/O
25	F	CD, bowel obstruction	6	Ileocaecal resection	B2/O
24	F	CD, ileosigmoid fistula+bowel obstruction	3	Ileocaecal resection	B3/O
21	M	CD+bowel obstruction	11	Resection of middle portion of small intestine	B2/I
26	M	CD+bowel obstruction	5	Ileocecal resection
21	F	CD+bowel obstruction	6	Resection of small intestine	B2/I
CD-GC group
24	F	CD, ileosigmoid fistula	3	Ileocaecal resection	B3/O
29	M	CD, right and transverse colon+bowel obstruction	4	Ileocolonic resection	B2/C
27	M	CD, bowel obstruction	15	Right ileocolonic resection	B2/C
38	M	CD, bowel obstruction	9 mo	Ileocecal resection	B2/O
36	F	CD, right and left colon	6	Ileocolonic resection	B1/C
24	F	CD, perineal lesions+bowel obstruction	4	Ileocecal resection	B2/O
28	F	CD, bowel obstruction	6	Ileocecal resection	B2/O
34	M	CD, bowel obstruction	2	Ileal and ileocaecal resection	B2/I
20	M	CD, bowel obstruction	3	Ileocaecal resection	B2/O
30	M	CD, bowel obstruction	3	Right colectomy	B2/C

The control group is defined in materials and methods; CD group, patients with Crohn’s disease not treated with glucocorticoids; CD-GC group, patients with Crohn’s disease treated with glucocorticoids.

B, behaviour status (non-stricturing non-penetrating (B1), stricturing (B2), penetrating (B3)) according to the Vienna classification.¹⁹

T, tissue origin of the portion of specimen studied (I, ileal; O, ileocaecal; C, colonic).