Table 3.

Effect of regenerating agents RG1503 and RG1192 on total collagen production in the bowel of patients with Crohn’s disease (CD)

	Protein production (total dpm/µg proline)	Collagen production (102 dpm hydroxy (3H) pro/mg collagen)
Control group	12 900 (1900)	1750 (220)
CD group	15 800 (2600)	6200 (890)***
CD group+RG1503	13 800 (2200)	3090 (470)*†
CD group+RG1192	15 900 (2400)	5020 (780)**
CD-GC group	14 200 (2100)	3700 (560)**
CD-GC group+RG1503	14 300 (2300)	2450 (380)‡
CD-GC group+RG1192	13 700 (2200)	3050 (420)*

Control, CD, and CD-GC groups as described in table 1 ▶.

RGTA treatment of normal intestinal tissue (control group) did not significantly change total collagen production (data not shown).

*p<0.05, **p<0.01, ***p<0.001 compared with the control group.

†p<0.05 between RGTA treatment and no RGTA treatment of specimens from the CD group.

‡p<0.05 between RGTA treatment and no RGTA treatment of specimens from the CD-GC group.