(A) Incidence of large (greatest diameter >1.0 mm), (B) medium (greatest diameter 0.5–1.0 mm), and (C) small (greatest diameter <0.5 mm) polyps in the colon. Colonic neoplasms were induced with 1,2-dimethylhydrazine, and mice then underwent a treatment free interval of two or three months before daily treatment for 10 days or one month with native glucagon-like peptide 2 (GLP-2), Gly2-GLP-2, or phosphate buffered saline (controls). *p<0.05, **p<0.01 versus controls; †p<0.05 versus native GLP-2. In (C), numerous small sized tumours formed larger conglomerates which made it impossible to count the exact number in the group of 3MO Gly-2-GLP-2 mice.