Table 5.
Helicobacter pylori eradication with triple therapy (proton pump inhibitor-clarithromycin-metronidazole) according to susceptibility or resistance to both antibiotics
| Reference | Type of study | Type of treatment | Overall | Eradication rate | |||
| Metronidazole susceptible | Metronidazole resistant | ||||||
| Clarithromycin resistant | Clarithromycin susceptible | Clarithromycin resistant | Clarithromycin susceptible | ||||
| Bazzoli112 | Randomised | OCT | 91.3 % (21/23) | 0 | 18/18 | 0/1 | 3/4 |
| Damman14 | Randomised | PCM | 85.1% (160/188) | 0/3 | 123/125 | 0/1 | 37/59 |
| Ellenrieder113 | Successive | PCM | 92.8% (78/84) | 2/3 | 63/67 | 0 | 13/14 |
| Hurenkamp114 | Randomised | OCM | 100% (74/74) | 1/1 | 57/57 | 0 | 16/16 |
| Lind25 | Randomised | OCM | 89.4% (102/114) | 4/6 | 73/75 | 0 | 25/33 |
| Pilotto109 | Randomised | PCM | 82.8% (29/35) | 2/3 | 24/25 | 0 | 3/7 |
| Poon110 | Randomised | LCM | 73.5% (25/34) | 0/2 | 15/16 | 0/3 | 10/13 |
| Savarino115 | Randomised | OCM | 73.1% (30/41) | 2/4 | 18/20 | 0/2 | 10/15 |
| Total | 50.0% (11/22) | 97.0% (391/403) | 0/7 | 72.6% (117/161) | |||
O, omeprazole; L, lanzoprazole; P, pantoprazole; C, clarithromycin; M, metronidazole; T, tinidazole.