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. 2004 Nov;53(11):1610–1616. doi: 10.1136/gut.2003.037580

Table 2.

 Short chain fatty acids, lactate, and succinate concentrations (mean (SEM) mM) in batch culture media with and without 1.5% w/v added prebiotic over 24 hours

Time (h) Acetate Propionate Butyrate Valerate Caproate Lactate Succinate
Con Pre Con Pre Con Pre Con Pre Con Pre Con Pre Con Pre
0 13 (1.2) 13 (1.2) 5 (0.7) 5 (0.7) 3 (0.7) 3 (0.7) 0.7 (0.2) 0.7 (0.2) 0.7 (0.2) 0.7 (0.2) 1.7 (04) 1.7 (0.4) 1.2 (0.5) 1.2 (0.5)
3 43 (4.1) 76 (13.5) 17 (3.3) 22 (4.9) 14 (2.9) 17 (3.3) 2.3 (0.7) 2.2 (0.6) 1.3 (0.5) 1.4 (0.4) 4.8 (1.9) 12 (3.0) 3.3 (2.4) 5.3 (2.7)
6 69 (4.9) 160 (20.4) 28 (3.3) 48 (16.7) 29 (4.5) 43 (8.2) 7 (2.4) 4.2 (1.4) 3.6 (1.8) 2.1 (1.1) 3.1 (1.9) 14 (8.0)* 3.0 (2.4) 5.4 (3.4)
12 90 (4.1) 200 (13.9)* 40 (2.4) 65 (18.4) 42 (2.0) 89 (5.3)* 18 (4.9) 20 (4.9) 7.4 (2.3) 11 (6.5) 3.5 (2.9) 26 (9.4)* 4.0 (3.4) 7.4 (6.8)
24 99 (5.3) 208 (13.5)* 45 (3.7) 57 (8.9) 54 (4.1) 96 (2.4)* 23 (5.3) 17 (4.5) 10 (2.9) 23 (10.2)

Con, control; Pre, prebiotic.

Significantly different from control, *p<0.001.