Table 3.
Serum levels of AST and ALT in wild type and SMP8-IGF-I mice after CCl4 administration
| 0 hours | 24 hours | 48 hours | 72 hours | |
| AST | ||||
| WT | 20 (2) | 32580 (1957) | 8087 (487) | 2255 (366) |
| SMP8-IGF-I TG | 21 (6) | 24020 (4951) | 2507 (158)* | 1167 (479)* |
| ALT | 0 hours | 24 hours | 48 hours | 72 hours |
| WT | 29 (8) | 54600 (1693) | 7623 (1051) | 1880 (253) |
| SMP8-IGF-I TG | 33 (7) | 42100 (3864) | 4780 (501)* | 520 (178) |
Values are expressed as IU/l and represent the mean (SEM) obtained from three to six mice in each group. *p<0.05 compared with the respective group of WT mice.