Changes in body weight after administration of phosphate buffered saline (PBS) or 2,4,6-trinitrobenzene sulphonic acid (TNBS). The groups were: PBS instilled 0.9% normal saline (NS) treated (n = 5) mice, PBS instilled losartan (Lsr) treated (n = 5) mice, TNBS instilled NS treated (n = 7) mice, and TNBS instilled Lsr treated (n = 9) mice. Results are expressed as mean (SEM). *Significant difference versus PBS instilled NS treated mice; †significant difference versus PBS instilled Lsr treated mice.