Histological findings in the colon three days after administration of phosphate buffered saline (PBS) or 2,4,6-trinitrobenzene sulphonic acid (TNBS) in the subcutaneous administration study. (A, B) 0.9% Normal saline (NS) treated PBS instilled mice, (C, D) NS treated TNBS instilled mice, (E, F) losartan (Lsr) treated PBS instilled mice, and (G, H) Lsr treated TNBS instilled mice. Magnification: A, C, E, G ×25; B, D, F, H ×100.