Table 4.
Studies on antibiotic prophylaxis for gastroenterology haemorrhage
| Reference | n | Randomised study | Antibiotic | Prevention of infection | Survival |
| Primary prophylaxis | |||||
| Rimola (1985)54 | 140 | Yes | Gentamycin + vancomycin + nystatin | Yes | Not assessed |
| Soriano (1992)55 | 119 | Yes | Norfloxacin | Yes | Unchanged |
| (The use of norfloxacin was more cost effective compared with placebo) | |||||
| Blaise (1994)56 | 91 | Yes | Ciprofloxacin + amoxicillin/clavulanic acid | Yes | Improved |
| Pauwels (1996)57 | 119 | Yes | Ciprofloxacin + amoxicillin/clavulanic acid | Yes | Unchanged |
| Sabats (1998)58 | 56 | Yes | Oral norfloxacin ± IV ceftriaxone | Yes | Not assessed |
| (Addition of IV ceftriaxone did not give added protection against bacterial infection) | |||||
| Hsieh (1998)59 | 120 | Yes | Ciprofloxacin | Yes | Not assessed |
| Secondary prophylaxis | |||||
| Hou (2004)36 | 120 | Yes | Ofloxacin | Yes | Not assessed |